Mejia-Santana, Collins R., Doud E.H., and Landeta C. Disulfide bonds are required for cell division, cell envelope biogenesis and antibiotic resistance proteins in mycobacteria.
Chavez D.*, Amarquaye G. N.*, Mejia-Santana A., Dyotima, Ryan K., Zeng L., and Landeta C. Warfarin analogs target disulfide bond-forming enzymes and suggest a residue important for quinone and coumarin binding. 2024. J Biol Chem. 2024 Jun;300(6):107383.https://www.jbc.org/article/S0021-9258(24)01884-2/fulltext.
Dyotima*, Abulaila S.*, Mendoza J., Landeta C. Development of a sensor for disulfide bond formation in diverse bacteria. 2024. J. Bacteriol. Mar 13. https://doi.org/10.1128/jb.00433-23
Antibiotic potentiation and inhibition of cross-resistance in pathogens associated with cystic fibrosis. Kadeřábková N., Furniss R. C. D., Maslova E., Eisaiankhongi L., Bernal P., Filloux A., Landeta C, Gonzalez D, McCarthy R. R., Mavridou D. A. I. 2023. eLife12:RP91082. https://doi.org/10.7554/eLife.91082.1
Landeta C., and Mejia-Santana A. Union Is Strength: Target-Based and Whole-Cell High-Throughput Screens in Antibacterial Discovery. 2022. J. Bacteriol. Apr 19;204(4):e0047721. doi: 10.1128/JB.00477-21
Prior to IU
Landeta C., McPartland L., Tran N. Q., Meehan B. M., Zhang Y., Tanweer Z., Wakabayashi S., Rock J., Rubin E. J., Lory S., Pier G., Dana Boyd, and Beckwith J. Inhibitors of Pseudomonas aeruginosa and Mycobacterium tuberculosis disulfide bond forming enzymes. 2019. Mol. Microb 111(4):918-937. PDF
Ke N., Landeta C., Wang X., Boyd D., Eser M., Beckwith J. Identification of the thioredoxin partner of VKOR in mycobacterial disulfide bond formation. 2018. J Bacteriol. 200(16): e00137-18. PDF
Landeta C., Boyd D., and Beckwith J. Disulfide bond formation in prokaryotes. 2018. Nature Microbiol. 3:270-280. PDF
Hibender S.*, Landeta C.*, Berkmen M., Beckwith J., and Boyd D. Aeropyrum pernix Membrane Protein VKOR Promotes Protein Disulfide Bond Formation in Two Subcellular Compartments. 2017. Microbiology 163:1864-1879. PDF
Meehan B. M., Landeta C., Boyd D., Beckwith J. The Disulfide Bond Formation Pathway is Essential for Anaerobic Growth of Escherichia coli. 2017. J. Bacteriol. 199(16): e00120-17. PDF
Landeta C., Meehan B. M., McPartland L., Ingendahl L., Hatahet F., Tran N.Q., Boyd D., and Beckwith J. Inhibition of virulence-promoting disulfide bond formation enzyme DsbB is blocked by mutating residues in two distinct regions. 2017. J. Biol. Chem. 292(16):6529–6541. PDF
Meehan B. M., Landeta C., Boyd D., and Beckwith J. 2017. The Essential Cell Division Protein FtsN Contains a Critical Disulfide Bond in a Non-essential Domain. Mol. Microbiol. Mol. Microbiology. 103 (3):413-422. PDF
Landeta C.*, Blazyk J.L.*, Hatahet F.*, Meehan B.M., Eser M., Myrick A., Bronstain L., Minami S., Arnold H., Ke N., Rubin E.J., Furie B.C. Furie B., Beckwith J., Dutton R., and Boyd D. Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria. 2015. Nat. Chem. Biol. 11 (4): 292-298. PDF
Landeta C., Dávalos A., Cevallos M. A., Geiger O., Brom S., and Romero D.. Plasmids with a chromosome-like role in Rhizobia. 2011. J. Bacteriol. 193: 1317- 1326. PDF